Muscle echogenicity is increased in fetuses with spina bifida aperta

Venous Outflow of the Brain in Spina Bifida Aperta

Altered Expression of 14-3-3ζ Protein in Spinal Cords of Rat Fetuses with Spina Bifida Aperta

BACKGROUND A large number of studies have confirmed that excessive apoptosis is one of the reasons for deficient neuronal function in neural tube defects (NTDs). A previous study from our laboratory used 2-D gel electrophoresis to demonstrate that 14-3-3ζ expression was low in the spinal cords of rat fetuses with spina bifida aperta at embryonic day (E) 17. As a member of the 14-3-3 protein fam...

Enhanced expression of collapsin response mediator protein 4 in spinal cords of rat fetuses with spina bifida aperta

Neural tube defects (NTDs) are severe congenital malformations that result from incomplete neurulation of the central nervous system. While collapsin response mediator protein 4 (CRMP-4) plays a critical role in the regulation of neurulation, information regarding the temporal expression of CRMP-4 during embryonic development of the spinal cord has yet to be reported. We therefore investigated ...

Degree of genetic homozygosity and distribution of AB0 blood types among patients with spina bifida occulta and spina bifida aperta

INTRODUCTION Assuming that spina bifida (SB) is a genetically controlled disease, the aim of our study was to evaluate the degree of genetic homozygosity and the distribution of AB0 blood types among patients with SB occulta and SB aperta by the homozygously recessive characteristics (HRC) test. MATERIAL AND METHODS Our study included an analysis of the presence, distribution and individual c...

Valgus deformity of the ankle in children with spina bifida aperta.

Valgus deformity of the hindfoot can occur at the subtalar joint, the ankle joint, or at both sites. In children suffering from spina bifida, the ankle is often the main site of deformity. Thirty-five ankles with valgus deformity of the hindfoot were studied in 23 children with spina bifida. A radiological triad was observed in all patients: shortening of the fibula, lateral wedging of the dist...